Senior Scientist II, Analytical Development

Company: AbbVie
Location: San Diego
Posted on: April 2, 2026

Job Description:

Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube. Job Description We seek a Senior Scientist II, Analytical Development to join an experienced, fast-paced and collaborative team. This position will be primarily responsible for guiding the biophysical analytical strategy and developing novel analytical methods for characterizing AbbVies mRNA-based targeted lipid nanoparticles (tLNPs) pipeline. This role will focus on developing novel biophysical methods for characterizing mRNA, lipids, and plasmids. Working collaboratively across discovery research, this position will develop novel characterization methods to support process/product understanding, expansion of the mRNA/tLNP platform and pipeline, and build structure-activity relationships. Responsibilities & Duties: Develop novel biophysical methods to characterize mRNA drug substance, including but not limited to LC, CE, LC-MS, MALLS, mass photometry, and plate-based assays Improve plasmid characterization and build relationships to mRNA quality Support product characterization for tLNP platform/formulation development and lead candidate selection Lead mass-spec characterization of oligonucleotides, proteins, and lipids Support characterization of lipid content and related impurities Support implementation of automation/high throughput (HTP) workflows and in-process analytical methods for routine and non-routine testing Represent functional area in cross-functional pipeline and technology development teams Support method transfer and qualifications as needed Draft technical reports and documents as needed Qualifications Generally met with a PhD with 4 years related experience, Masters with 10 years experience, or Bachelors with 12 years of experience Degree in Biochemistry, Chemistry, Bioengineering, Chemical Engineering or related field with proven technical and leadership track record developing analytical characterization methods for biologics (e.g. antibodies, mRNA, etc) is required Expertise with LC-MS is required Experience developing analytical methods for oligonucleotides (e.g. LC, CE, MS, MALLS, etc) and lipids is required. Experience with plasmid characterization is strongly preferred Experience with method transfer and qualification is preferred Strong proficiency authoring and reviewing technical reports Experience with stability and comparability studies is preferred Strong communication skills, both written and verbal, with a demonstrated capacity to thrive in collaborative, team-driven environments. Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law: The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees. This job is eligible to participate in our short-term incentiveprograms. Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html

Keywords: AbbVie, Corona , Senior Scientist II, Analytical Development, Healthcare , San Diego, California